Benefits and risks of antidepressant medication

A recent analy­sis of many pub­lished research stud­ies con­clud­ed that tak­ing anti-depres­sants results in a 33% rise in mor­tal­i­ty.

Like many oth­er drugs, anti-depres­sants inter­fere with mul­ti­ple bio­chem­i­cal process­es in the body, some­times in ways we don’t ful­ly under­stand. There can be unpre­dictable inter­ac­tions from these bio­chem­i­cal dis­rup­tions, and they can result in sig­nif­i­cant ill­ness, even though the ill­ness is nev­er iden­ti­fied as a “side effect.”

At the same time, a sys­tem­at­ic review of anti-depres­sant use as com­pared to the use of cog­ni­tive behav­ioral ther­a­py stat­ed “Over­all, the avail­able evi­dence indi­cates that sec­ond gen­er­a­tion anti-depres­sants (SSRI’s) and Cog­ni­tive Behav­ioral Ther­a­py do not dif­fer sig­nif­i­cant­ly in symp­to­matic relief as first-step treat­ments for adult out­pa­tients with mod­er­ate to severe major depres­sive dis­or­der.”

Inform your­self before accept­ing phar­ma­ceu­ti­cal treat­ment options. Often­times there are safer, more effec­tive alter­na­tives.


Deepen Your Body of Knowledge

Are anti­de­pres­sants effec­tive?

Exer­cise treat­ment for depres­sion


About Ronald Lavine, D.C.

Dr. Lavine has more than thirty years' experience helping patients alleviate pain and restore health using diverse, scientifically-based manual therapy and therapeutic exercise and alignment methods. His website,, provides more information about his approach. Please contact him at or at 212-400-9663.
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